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MAGEL2 (MAGE-like 2) Blocking Peptide (the C terminal of MAGEL2)(100ug)

MAGEL2 (MAGE-like 2) Blocking Peptide (the C terminal of MAGEL2)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-MAGEL2 Antibody (ARP59891_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP59891
Size: 100ug
Weight: 58kDa
Gene: 54551
Format: Lyophilized powder
Target: Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.
Alternative names: NDNL1; nM15
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