Reactivities: | Human, Mouse |
Presku: | AAP32010 |
Size: | 100ug |
Weight: | 18kDa |
Gene: | 17134 |
Format: | Lyophilized powder |
Target: | Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. Mafg activates globin gene expression when associated with NF-E2 and may be involved in signal transduction of extracellular H+. |
Alternative names: | AA545192; C630022N07Rik |