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Mafa (v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)) Blocking Peptide (the c terminal of Mafa)(100ug)

Mafa (v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)) Blocking Peptide (the c terminal of Mafa)(100ug)

This is a synthetic peptide designed for use in combination with anti-Mafa Antibody(ARP37614_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Mouse

Format

Lyophilized powder

Presku

AAP37614

Target

Mafa acts as a transcriptional factor. Mafa specifically binds the insulin enhancer element RIPE3b. Mafa cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Mafa regulates the insulin gene transcription. Mafa is involved either as an oncogene or as a tumor suppressor, depending on the cell context.

Weight

37kDa

Gene Id

378435

Alternative Names

RIPE3b1

SUPPLIER INFO

Aviva Systems Biology Incorporated

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