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MAF (v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)) Blocking Peptide (the middle region of protein) (100ug)

MAF (v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)) Blocking Peptide (the middle region of protein) (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-MAF antibody (Catalogue #: P100617_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP30933
Size: 100 ug
Weight: 42kDa
Gene: 4094
Format: Lyophilized powder
Target: MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Alternative names: MGC71685
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