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LYN (2H8D) Antibody
ABBIOTEC

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ABBIOTEC

Cat no: 252697

LYN (2H8D) Antibody

Lyn (p53/56 Lyn) is a membrane-associated protein tyrosine kinase (PTK) mostly e, Xenopus/Amphibian,pressed in hemopoietic cells which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis. A member of the Src family of PTKs, there are two known isoforms for Lyn which plays an indispensable role in the Fc epsilon RI (Fcer1) and the B-cell IgM receptor signaling pathway and is essential for Syk activation and Lat phosphorylation after Fcer1 aggregation and can also phosphorylate Tec on multiple residues. Lyn can also be regulated by IL-2 and IL-3. Lyn is a member of the src family of non-receptor protein tyrosine kinases,Porcineredominantly e, Xenopus/Amphibian,pressed in haematopoietic tissues. Like all members of the src family, lyn is thought to participate in signal transduction from cell surface receptors that lack intrinsic tyrosine kinase activity. It is associated with a number of cell surface receptors including the B cell antigen receptor and immunoglobulin E receptor (FceRI).

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SPECIFICATIONS

Catalog Number

252697

Size

0.1 ml

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of LYN e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG2b

Accession

P07948

Clonality

2H8D7

Additional Info

Lck/Yes-related novel protein tyrosine kinase; V-yes-1; Yamaguchi sarcoma viral related oncogene homolog; p53Lyn; p56Lyn; JTK8; FLJ26625

SUPPLIER INFO

ABBIOTEC

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