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LRRFIP1 Antibody (OAPB01261)

LRRFIP1 Antibody (OAPB01261)

LRRFIP1, also known as GC-binding factor 2 (GCF2), is a 738 amino acid transcriptional repressor that mainly plays a cytoskeletal role. It is primarily localized in the cytoplasm and preferentially binds to GC-rich dsDNA, but will also bind directly to dsRNA as well. The RNA binding domain encompasses a lysine-rich motif. LRRFIP1 interacts with the mammalian Flightless I (Fli-I) and is a key component in the cytoskeletal regulation of platelet function. LRRFIP1 and the related protein LRRFIP2 may modulate canonical WNT signaling and mediate the IRF3-induced production of type I interferon via a beta-catenin-dependent pathway.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Presku

OAPB01261

Target

Leucine rich repeat interacting protein 1

Alternative Names

Leucine rich repeat interacting protein 1; TAR RNA-interacting protein; TRIP; FLAP-1; FLIIAP1; GC-binding factor 2; GCF2

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