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LRDD (leucine-rich repeats and death domain containing) Blocking Peptide (the middle region of LRDD)(100ug)

LRDD (leucine-rich repeats and death domain containing) Blocking Peptide (the middle region of LRDD)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-LRDD Antibody(ARP57270_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP57270
Size: 100ug
Weight: 83kDa
Gene: 55367
Format: Lyophilized powder
Target: The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alternative names: DKFZp434D229; MGC16925; PIDD
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