Reactivities: | Mouse |
Presku: | AAP47360 |
Size: | 100ug |
Weight: | 60kDa |
Gene: | The peptide is characterized by mass spectroscopy |
Format: | Lyophilized powder |
Target: | Lpcat2 possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. It is involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). It also converts lyso-PAF to 1-alkyl-phosphatidylcholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. |
Alternative names: | A330042H22; Aytl1; LPCAT2; lpafat1 |