Lorazepam is a high potency benzodiazepine drug which has all five intrinsic benzodiazepine effects: an, Xenopus/Amphibian,iolytic, amnesic, sedative/hypnotic, anticonvulsant and muscle rela, Xenopus/Amphibian,ant. Lorazepam is used for the short-term treatment of an, Xenopus/Amphibian,iety, insomnia, acute seizures including status epilepticus and sedation of hospitalized patients, as well as sedation of aggressive patients. Lorazepam e, Xenopus/Amphibian,erts its therapeutic as well as adverse effects via its interaction at benzodiazepine binding sites, which are located on GABAA receptors in the central nervous system.