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LIN28 (lin-28 homolog (C. elegans)) Blocking Peptide (the N terminal of protein) (100ug)

LIN28 (lin-28 homolog (C. elegans)) Blocking Peptide (the N terminal of protein) (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-LIN28 antibody (Catalogue #: ARP34477_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP34477
Size: 100 ug
Weight: 23kDa
Gene: 79727
Format: Lyophilized powder
Target: LIN28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. The association of LIN28 with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. IT binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. LIN28 is Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression.
Alternative names: CSDD1; FLJ12457; LIN-28; LIN28A; ZCCHC1
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