Reactivities: | Human |
Presku: | AAP65340 |
Size: | 100ug |
Weight: | 45kDa |
Gene: | 11026 |
Format: | Lyophilized powder |
Target: | Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function. LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor. |
Alternative names: | CD85E; HM31; HM43; ILT6; LIR-4; LIR4; e3 |