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LIGHT Recombinant Protein (0.003 mg)

LIGHT Recombinant Protein (0.003 mg)

LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFkappaB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant human LIGHT has a calculated mass of 19.3 kDa containing 177 amino acid residues. Due to glycosylation LIGHT migrates between 20.0-22.5 kDa by SDS-PAGE under non-reducing conditions.

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SPECIFICATIONS

Size

0.003 mg

Presku

OPPB00203

Alternative Names

TNFSF14; HVEM-L

SUPPLIER INFO

Aviva Systems Biology Incorporated

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