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LEF1 (Human) cDNA (1ug)

LEF1 (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human LEF1 is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-LEF1 polyclonal antibody.
Presku: ANA10567
Size: 1ug
Gene: 51176
Target: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Alternative names: TCF10; TCF7L3; FLJ46390; TCF1ALPHA; DKFZp586H0919; LEF-1
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