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LEAF(TM) Purified anti-mouse/human CD11b

LEAF(TM) Purified anti-mouse/human CD11b

Cat no: 101231

Supplier: BioLegend
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CD11b is a 170 kD glycoprotein also known as alphaM integrin, Mac-1 alpha subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (beta2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
Catalogue number: 101231
Reactivities: Human, Mouse
Hosts: Rat
Applications: Block/Neutralize/Inhibit, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
Size: 1 mg
Clone: M1/70
Gene: 16409, 3684
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.25 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration: 1 mg/ml
Antigen: C57BL/10 splenocytes
Isotype: Rat IgG2b, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Integrin aM, alphaM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR
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