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LEAF(TM) Purified anti-human CD49e

LEAF(TM) Purified anti-human CD49e

Cat no: 328004

Supplier: BioLegend
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CD49e is a type I integral membrane glycoprotein, known as alpha5 integrin, VLA-5 alpha chain. It forms noncovalent heterodimer with integrin beta1 (CD29). CD49e contains two disulfide-linked subunits of 135 kD and 24 kD, and is mainly expressed on thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, and some myeloid leukemia cells. CD49e/CD29 complex binds to fibronection and neural adhesion molecule L1. It mediates monocytes migration, involves in the regulation of cells survival and apoptosis, and co-stimulates T cell activation.
Catalogue number: 328004
Reactivities: Human
Hosts: Mouse
Applications: Block/Neutralize/Inhibit, ELISA, Flow Cytometry, Immunoprecipitation
Size: 500 microg
Clone: NKI-SAM-1
Gene: 3678
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 1.0 microg per 106 cells in 100 microl. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions
Concentration: 1 mg/ml
Antigen: U937 cells
Isotype: Mouse IgG2b, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: alpha5 integrin, VLA-5 alpha chain, Integrin alpha5
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