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LEAF(TM) Purified anti-human CD284 (TLR4)

LEAF(TM) Purified anti-human CD284 (TLR4)

Cat no: 312808

Supplier: BioLegend
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Toll-like receptors are type I transmembrane signaling receptors. They are primordial pathogen-recognition proteins that function as sentinels for the innate immune system. TLR4, also known as CD284, is a 110 kD protein which is expressed on monocytes/macrophages, endothelial cells, and at low levels on B cells and granulocytes. In association with a secretory molecule, MD2, TLR4 has been recognized as critical for host recognition of bacterial LPS. HTA125 antibody is useful for flow cytometric analysis and is able to block LPS-induced cytokine production.
Catalogue number: 312808
Reactivities: Human
Hosts: Mouse
Applications: Block/Neutralize/Inhibit, Flow Cytometry, Immunofluorescence, Immunohistochemistry
Size: 500 microg
Clone: HTA125
Gene: 7099
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?2.0 microg per million cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C. This LEAF(TM) solution contains no preservative; handle under aseptic conditions.
Concentration: 1 mg/ml
Antigen: Ba/F3 cell line expressing human TLR4
Isotype: Mouse IgG2a, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Toll like Receptor 4, TLR-4
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