LDL MDA-treated (10G10) Antibody

Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions o, Xenopus/Amphibian,idatively modified LDL is found and o, Xenopus/Amphibian,idized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. O, Xenopus/Amphibian,idized LDL may be a marker of atherosclerosis but the precise changes in o, Xenopus/Amphibian,idized LDL are not well described. MDA-treated LDL appear to be different from LDL o, Xenopus/Amphibian,idized by other means. This antibody reacts with MDA-treated LDL but not with native LDL.