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LAL (9G7F) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252646

LAL (9G7F) Antibody

LAL (Lysosomal acid lipase) is a 378-amino acid (~43-54 kDa) protein. It is found in the lysosomes to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. It is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs,Porcinearticularly in liver, spleen, the adrenal and the hemopoietic system, also in the intestine as well as in the lymph nodes, lungs, testes and ovaries.

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SPECIFICATIONS

Catalog Number

252646

Size

0.1 mg

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of LAL e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG2a

Accession

P38571

Clonality

9G7F12,7G6D7

Additional Info

Lysosomal acid lipase/cholesteryl ester hydrolase; Acid cholesteryl ester hydrolase; LAL; Cholesteryl esterase; Lipase A; Sterol esterase

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