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KRT8 (Human) cDNA (1ug)

KRT8 (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human KRT8 is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-KRT8 polyclonal antibody.
Presku: ANA11504
Size: 1ug
Gene: 3856
Target: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
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