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KRT15 (6E7) Antibody
ABBIOTEC

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ABBIOTEC

Cat no: 252936

KRT15 (6E7) Antibody

KRT15 (Cytokeratin-15) is a member of the keratin protein family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 15 is a type I keratin without a defined type II partner. Keratin 15 is e, Xenopus/Amphibian,pressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. E, Xenopus/Amphibian,pression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars. Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 e, Xenopus/Amphibian,pression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype.

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SPECIFICATIONS

Catalog Number

252936

Size

0.1 ml

Applications

FC, IF

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of KRT15 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG2a

Accession

P19012

Clonality

6E7

Additional Info

Keratin, type I cytoskeletal 15; Cytokeratin-15; CK-15; Keratin-15; K15; KRTB; KRT15

SUPPLIER INFO

ABBIOTEC

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