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KPNA3 Antibody (OAPB01181)

KPNA3 Antibody (OAPB01181)

Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA3, the alpha subunit 3 of karyopherin, is silimar to human KPNA2, suggesting that KPNA3 may be involved in the nuclear transport system. It is ubiquitously expressed and recent studies have shown that human KPNA3 may be associated with schizophrenia.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Presku

OAPB01181

Target

Importin alpha 4

Alternative Names

KPNA3; Karyopherin alpha nucleoprotein interactor 3; importin alpha 4; IPOA4; importin-alpha-Q2; QIP2; SRP4

SUPPLIER INFO

Aviva Systems Biology Incorporated

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