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KPNA2 Antibody (OAPB01180)

KPNA2 Antibody (OAPB01180)

Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA2 is the alpha subunit 2 of karyopherin, which forms a complex with importin subunit beta-1 and functions as a cargo carrier that transports various complexes from cytoplasm into nucleus. It is ubiquitously expressed and contains an IBB/importin beta domain, ten Armadillo repeats that bind

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Presku

OAPB01180

Target

Importin alpha 2

Alternative Names

KPNA2; Karyopherin alpha nucleoprotein interactor 2; Importin alpha2; IPOA1; RAG cohort protein 1; RCH1; SRP1; QIP2

SUPPLIER INFO

Aviva Systems Biology Incorporated

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