Presku: | AAP45680 |
Size: | 100 ug |
Weight: | 72kDa |
Gene: | 3827 |
Format: | Lyophilized powder |
Target: | Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII and inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects such as influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, etc. |
Alternative names: | BDK; KNG |