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KLRC1 (killer cell lectin-like receptor subfamily C, member 1 ) Blocking Peptide (the C terminal of KLRC1)(100ug)

KLRC1 (killer cell lectin-like receptor subfamily C, member 1 ) Blocking Peptide (the C terminal of KLRC1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-KLRC1 Antibody (ARP61288_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP61288
Size: 100ug
Weight: 24kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
Alternative names: CD159A; MGC13374; MGC59791; NKG2; NKG2A
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