Reactivities: | Rat |
Presku: | AAP39507 |
Size: | 100ug |
Weight: | 62kDa |
Gene: | The peptide is characterized by mass spectroscopy |
Format: | Lyophilized powder |
Target: | Klhl12 serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. It negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3. |
Alternative names: | C3ip1; MGC93127 |