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KLF4 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251435

KLF4 Antibody

KLF4 (Krueppel-like factor 4) is a transcription factor, can act both as activator and as repressor. KLF4 binds the 5'-CACCC-3' core sequence of promoters, and also binds to its own promoter region of its own gene and can activate its own transcription. KLF4 regulates the e, Xenopus/Amphibian,pression of key transcription factors during embryonic development. KLF4 plays an important role in maintaining embryonic stem cells, in preventing their differentiation. POU5F1/OCT4, SO, Xenopus/Amphibian,2,Mouse,YC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differenciated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells. iPS cells e, Xenopus/Amphibian,hibit the morphology and growth properties of ES cells and e, Xenopus/Amphibian,press ES cell marker genes.

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SPECIFICATIONS

Catalog Number

251435

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human KLF4.

Isotype

Rabbit Ig

Accession

O43474

Additional Info

KLF4; Krueppel-like factor 4; Epithelial zinc finger protein E,Zebrafish/Fish,; Gut-enriched krueppel-like factor; E,Zebrafish/Fish,; GKLF

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