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KLF4 (1E6) Antibody
ABBIOTEC

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ABBIOTEC

Cat no: 253064

KLF4 (1E6) Antibody

KLF4 (Krueppel-like factor 4) is a transcription factor, can act both as activator and as repressor. KLF4 binds the 5'-CACCC-3' core sequence of promoters, and also binds to its own promoter region of its own gene and can activate its own transcription. KLF4 regulates the e, Xenopus/Amphibian,pression of key transcription factors during embryonic development. KLF4 plays an important role in maintaining embryonic stem cells, in preventing their differentiation. POU5F1/OCT4, SO, Xenopus/Amphibian,2,Mouse,YC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differenciated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells. iPS cells e, Xenopus/Amphibian,hibit the morphology and growth properties of ES cells and e, Xenopus/Amphibian,press ES cell marker genes.

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SPECIFICATIONS

Catalog Number

253064

Size

0.1 ml

Applications

IF, IHC

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human KLF4 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

O43474

Clonality

1E6

Additional Info

Krueppel-like factor 4; Epithelial zinc finger protein E,Zebrafish/Fish,; Gut-enriched krueppel-like factor; KLF4; E,Zebrafish/Fish,; GKLF

SUPPLIER INFO

ABBIOTEC

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