Presku: | AAP53325 |
Size: | 100 ug |
Weight: | 120kDa |
Gene: | 152831 |
Format: | Lyophilized powder |
Target: | KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21. |
Alternative names: | BKL; MGC142213 |