Formalin-fixed, paraffin-embedded tissue is useful for a variety of applications including the targeting of proteins, RNA, and DNA by means of Immunohistochemistry (IHC), in-situ hybridization (ISH) and fluorescence in-situ hybridization (FISH), respectively. Some tissue types may require extra attention as they may contain high levels of endogenous biotin, peroxidase, or autofluorescence.
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