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KCNQ4 (potassium voltage-gated channel, KQT-like subfamily, member 4) Blocking Peptide (the middle region of KCNQ4)(100ug)

KCNQ4 (potassium voltage-gated channel, KQT-like subfamily, member 4) Blocking Peptide (the middle region of KCNQ4)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-KCNQ4 Antibody(ARP35148_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP35148
Size: 100ug
Weight: 77kDa
Gene: 9132
Format: Lyophilized powder
Target: The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.
Alternative names: DFNA2; KV7.4
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