Home  >  Products  >  KCNQ2 (potassium voltage-gated channel, KQT-like subfamily, member 2) Blocking Peptide (the middle region of protein) (100ug)
KCNQ2 (potassium voltage-gated channel, KQT-like subfamily, member 2) Blocking Peptide (the middle region of protein) (100ug)

KCNQ2 (potassium voltage-gated channel, KQT-like subfamily, member 2) Blocking Peptide (the middle region of protein) (100ug)

Supplier: Aviva Systems Biology Incorporated
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
This is a synthetic peptide designed for use in combination with anti-KCNQ2 antibody (Catalogue #: ARP35457_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP35457
Size: 100 ug
Weight: 44kDa
Gene: 3785
Format: Lyophilized powder
Target: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by KCNQ2 and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.
Alternative names: BFNC; EBN; EBN1; ENB1; HNSPC; KCNA11; KV7.2; KVEBN1
See Full Product Listings >