Home  >  Products  >  KCNQ2 (potassium voltage-gated channel, KQT-like subfamily, member 2) Blocking Peptide (100ug)
KCNQ2 (potassium voltage-gated channel, KQT-like subfamily, member 2) Blocking Peptide (100ug)

KCNQ2 (potassium voltage-gated channel, KQT-like subfamily, member 2) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
This is a synthetic peptide designed for use in combination with anti-KCNQ2 antibody (Catalogue #: ARP35459_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP35459
Size: 100 ug
Weight: 43kDa
Gene: 3785
Format: Lyophilized powder
Target: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by the KCNQ2 gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).
See Full Product Listings >