Supplier:
Aviva Systems Biology IncorporatedKCNMA1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1) Blocking Peptide (the middle region of protein) (100ug)
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SPECIFICATIONS
Size
100 ug
Format
Lyophilized powder
Presku
AAP37677
Target
This protein is a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
Weight
131kDa
Gene Id
3778
Alternative Names
BKTM; DKFZp686K1437; KCa1.1; MGC71881; MaxiK; SAKCA; SLO; SLO-ALPHA; mSLO1
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