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KCNAB2 (Human) cDNA (1ug)

KCNAB2 (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human KCNAB2 is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-KCNAB2 polyclonal antibody.
Presku: ANA10987
Size: 1ug
Gene: 8514
Target: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Alternative names: AKR6A5; KCNA2B; HKvbeta2; KV-BETA-2; MGC117289; HKvbeta2.1; HKvbeta2.2
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