Supplier:
Aviva Systems Biology IncorporatedKCNA2 Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)
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SPECIFICATIONS
Size
200ug
Presku
APL10874
Target
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.
Weight
44
Gene Id
3737
Alternative Names
HK4; MK2; HBK5; NGK1; RBK2; HUKIV; KV1.2; MGC50217
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