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KCNA2 (Human) cDNA (1ug)

KCNA2 (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human KCNA2 is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-KCNA2 polyclonal antibody.
Presku: ANA10874
Size: 1ug
Gene: 3737
Target: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.
Alternative names: HK4; MK2; HBK5; NGK1; RBK2; HUKIV; KV1.2; MGC50217
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