Home  >  Products  >  ITM2C (integral membrane protein 2C ) Blocking Peptide (the middle region of ITM2C)(100ug)
ITM2C (integral membrane protein 2C ) Blocking Peptide (the middle region of ITM2C)(100ug)

ITM2C (integral membrane protein 2C ) Blocking Peptide (the middle region of ITM2C)(100ug)

Supplier: Aviva Systems Biology Incorporated
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
This is a synthetic peptide designed for use in combination with anti-ITM2C Antibody (ARP44631_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP44631
Size: 100ug
Weight: 30kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: ITM2C is a negative regulator of beta amyloid peptide production. ITM2C may inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor.ITM2C may play a role in TNF-induced cell death and neuronal differentiation.
Alternative names: BRI3; BRICD2C; E25; E25C; ITM3
See Full Product Listings >