Presku: | AAP37180 |
Size: | 100 ug |
Weight: | 55kDa |
Gene: | 27056 |
Format: | Lyophilized powder |
Target: | The activation of Toll-like receptors (TLRs) is central to innate and adaptive immunity. All TLRs use the adaptor MyD88 for signaling. IRF-5 is generally involved downstream of the TLR-MyD88 signalling pathway for gene induction of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-12 and tumour-necrosis factor-alpha. |