Recognizes common epitopes of alpha-A, -F, -D, -I1, -P human interferon subtypes; reacts with different antigenic epitope, than NK-2.YOK MAb (Celltech), Kd = 2.4 x 10 -10 M. Can be used for the detection of recombinant alpha-A, -F, - D, I1, -P interferon subtypes in two-site immunoassay and in affinity purification of recombinant interferons of alpha-A, -F, -D.