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Insulin Receptor-beta Antibody

Insulin Receptor-beta Antibody

Cat no: 250724

Supplier: ABBIOTEC
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Insulin Receptor-beta (INSR) binds insulin and has a tyrosine protein kinase activity. The short isoform has a higher affinity for insulin. The receptor mediates the metabolic functions of insulin. Receptor binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Defects in INSR are the cause of insulin resistance.
Catalogue number: 250724
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P06213
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human insulin receptor-beta.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit IgG
Additional info: Insulin receptor; Insulin receptor subunit beta; CD220 antigen; IR; INSR
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