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Insulin Receptor Antibody

Insulin Receptor Antibody

Cat no: 250721

Supplier: ABBIOTEC
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INSR binds insulin and has a tyrosine protein kinase activity. The short isoform has a higher affinity for insulin. The receptor mediates the metabolic functions of insulin. The receptor binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Defects in INSR are the cause of insulin resistance. This antibody is against the alpha subunit.
Catalogue number: 250721
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P06213
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human INSR-alpha.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Insulin receptor; CD220 antigen; IR; INSR
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