Integrin-linked protein kinase 1 (ILK-1) is a mediator of inside-out integrin signaling and a focal adhesion protein part of the ILK-PINCH comple, Xenopus/Amphibian,. This comple, Xenopus/Amphibian, is considered to be one of the convergence points of integrin and growth factor signaling pathways. It is implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. ILK-1 phosphorylates beta-1 and beta-3 integrin subunits on serine and threonine residues, as well as AKT1 and GSK3B. ILK-1 is strongly e, Xenopus/Amphibian,pressed in heart, skeletal muscle,Porcineancreas and kidney, and is weakly e, Xenopus/Amphibian,pressed in placenta, lung and liver.