Presku: | ANA10343 |
Size: | 1ug |
Gene: | 3579 |
Target: | IL8RB is the receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. IL8RB binds to IL-8 with high affinity. IL8RB also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. |
Alternative names: | CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB |