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IL6ST (interleukin 6 signal transducer (gp130, oncostatin M receptor) ) Blocking Peptide (the middle region of IL6ST)(100ug)

IL6ST (interleukin 6 signal transducer (gp130, oncostatin M receptor) ) Blocking Peptide (the middle region of IL6ST)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-IL6ST Antibody (ARP63223_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP63223
Size: 100ug
Weight: 35kDa
Gene: 3572
Format: Lyophilized powder
Target: The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis.
Alternative names: CD130; CDw130; GP130; GP130-RAPS; IL6R-beta
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