Reactivities: | Human |
Presku: | AAP63701 |
Size: | 100ug |
Weight: | 22kDa |
Gene: | 282617 |
Format: | Lyophilized powder |
Target: | This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). |
Alternative names: | IFNL3; IL-28B; IL28C |