Reactivities: | Human |
Presku: | AAP60746 |
Size: | 100ug |
Weight: | 16kDa |
Gene: | 59067 |
Format: | Lyophilized powder |
Target: | This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Alternative names: | IL-21; Za11 |