Reactivities: | Human |
Hosts: | Mouse |
Applications: | Western Blot |
Presku: | AMM00030 |
Size: | 100ug |
Weight: | 17kDa |
Gene: | 3605 |
Format: | Lyophilized powder |
Target: | IL-17 is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. |
Isotype: | Mouse IgG2a |
Alternative names: | IL17; CTLA8; IL-17; IL-17A; IL17A |