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IL-4 Recombinant Protein (0.002 mg)

IL-4 Recombinant Protein (0.002 mg)

IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant rat IL-4 is a 14.0 kDa globular protein containing 126 amino acid residues.

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SPECIFICATIONS

Size

0.002 mg

Presku

OPPB00364

Alternative Names

BCGF; BCDF; B cell stimulating factor (BSF-1)

SUPPLIER INFO

Aviva Systems Biology Incorporated

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