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IL 23 Human - Recombinant Human Interleukin-23 (2ug)

IL 23 Human - Recombinant Human Interleukin-23 (2ug)

Product Introduction: IL23 is composed of a subunit of the heterodimeric cytokine IL23 and the p40 subunit of interleukin 12 (IL12B). Interleukin-23 (IL-23) belongs to the IL-12 family and is produced by antigen presenting cells. IL-23 using IL12RB1 and IL-23R (specific for IL-23) can activate STAT and NF-?B pathways and stimulate the production of interferon-gamma. ). IL-23 is known to take a vital part in the inflammation process and is associated with auto immune diseases. However, unlike IL12, which acts primarily on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.
Product Description: IL-23 Human Recombinant produced in HEK 293 cells is a disulfide-linked heterodimer, containing one polypeptide chain p19 subunit containing 169 amino acids and one polypeptide chain IL-12B p40 subunit containing 306 amino acids, with the total molecular weight of 53kDa (not including glycosylation). The IL-23 is purified by proprietary chromatographic techniques.

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SPECIFICATIONS

Size

2ug

Format

IL-23 if supplied as a sterile filtered White lyophilized (freeze-dried) powder.

Presku

OOPA00061

Alternative Names

interleukin 23 alpha subunit p19; interleukin-12 subunit beta p40; SGRF; IL23P19; IL-23-A; interleukin-six; G-CSF related factor; JKA3 induced upon T-cell activation; interleukin 12B (natural killer cell stimulatory factor 2 cytotoxic lymphocyte maturatio

SUPPLIER INFO

Aviva Systems Biology Incorporated

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