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IL-13 Recombinant Protein (0.002 mg)

IL-13 Recombinant Protein (0.002 mg)

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. Recombinant rat IL-13 is a 12.3 kDa protein consisting of 113 amino acid residues.

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SPECIFICATIONS

Size

0.002 mg

Presku

OPPB00370

Alternative Names

NC300 (Human) P600 (Murine)

SUPPLIER INFO

Aviva Systems Biology Incorporated

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